Filling a GAP-An Optimized Probe for ER Ca~(2+) Imaging In Vivo

摘要

In this issue of Cell Chemical Biology, Navas-Navarro et al. (2016) demonstrate that fusion of engineered derivatives of the long-known jellyfish proteins green fluorescent protein (GFP) and aequorin yield optimized genetically encoded fluorescent probes for detecting Ca~(2+) signals within the endoplasmic reticulum (ER) of living animals.