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Synthesis and Biological Activity of Acylthiourea Derivatives Contain 1,2,3-thiadiazole and 1,3,4-thiadiazole

机译:1,2,3-噻二唑和1,3,4-噻二唑的酰基硫脲衍生物的合成及生物活性

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摘要

In order to investigate the biological activity of novel thiourea compounds, some novel 1,2,3-thiadiazole derivatives containing 1,3,4-thiadiazole were synthesized under phase transfer catalyzed condition (PEG-600) by multi-step reactions. The chemical structures of all compounds were established by H-1 NMR, FTIR, MS, and elemental analysis, and some of these compounds were investigated for fungicidal activity and plant growth regulatory activity. The bioassay results indicated that some of these compound exhibited moderate activities.
机译:为了研究新型硫脲化合物的生物活性,在相转移催化条件下(PEG-600),通过多步反应合成了一些含有1,2,3-噻二唑的新型1,2,3-噻二唑衍生物。通过H-1 NMR,FTIR,MS和元素分析确定了所有化合物的化学结构,并对其中一些化合物的杀真菌活性和植物生长调节活性进行了研究。生物测定结果表明,这些化合物中的一些表现出中等活性。

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