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Serovar distribution and antimicrobial susceptibility of swine Salmonella isolates from clinically ill pigs in diagnostic submissions from Indiana in the United States

机译:来自美国印第安纳州的诊断报告中来自临床患病猪的猪沙门氏菌分离株的血清分布和抗药性

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AIMS: To determine serovar distribution and levels of antimicrobial susceptibility of Salmonella isolated from clinically ill pigs in diagnostic submissions. METHODS AND RESULTS: A total of 197 Salmonella isolates were obtained by the Indiana Animal Disease Diagnostic Laboratory from 2003 to 2005. Minimal inhibitory concentrations (MICs) were determined using the standard microbroth dilution method. The top four serovars identified were Salm. enterica serovar Typhimurium variant Copenhagen, Salm. Derby, Salm. Choleraesuis var. Kunzendorf and Salm. Typhimurium. All isolates were susceptible to the fluoroquinolones tested except that eight isolates were intermediate to difloxacin. The isolates showed a low prevalence of resistance to trimethoprim/sulphadiazine (Sxt), gentamicin (G), ceftiofur (Cf) and cephalothin (Cp) with low MIC(50) value of
机译:目的:确定诊断性呈报中从临床患病猪中分离出的沙门氏菌的血清分布和抗药性水平。方法与结果:2003年至2005年,印第安纳州动物疾病诊断实验室共获得197株沙门氏菌分离株。采用标准微孔稀释法测定最低抑菌浓度(MIC)。识别出的前四名Serovar是Salm。肠球菌鼠伤寒变种哥本哈根,萨尔姆。德比,萨尔姆。霍乱弧菌Kunzendorf和Salm。鼠伤寒所有分离株都对所测试的氟喹诺酮类敏感,除了八个分离株在地氟沙星中间。分离株对甲氧苄氨嘧啶/磺胺二嗪(Sxt),庆大霉素(G),头孢噻呋(Cf)和头孢菌素(Cp)的耐药性低,MIC(50)值低至<或= 0.5、0.5、1和4 microg ml (-1)。他们显示出对四环素的高耐药性(T; 83.8%),对氨苄西林(55.8%),壮观霉素(42.6%),替卡西林(41.6%)和氟苯尼考(41.1%)的中度患病率。有更多的萨尔姆菌分离株。鼠伤寒,包括var。哥本哈根和萨尔姆。 Agona对阿莫西林/克拉维酸,氨苄青霉素,头孢噻呋和头孢菌素(AxApCfCp)具有多重抗药性。结论:猪沙门氏菌分离株对氟喹诺酮类,Sxt,G,Cf和Cp敏感,但对T耐药。研究的意义和影响:这些发现为处理猪群中临床沙门氏菌病的抗药性和耐药性提供了有用的信息。 。

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