An image fiber based fluorescent probe with associated signal processing scheme for biomedical diagnostics

摘要

A dual-modality image fiber based fluorescent probe that can be used for depth sensitive imaging and suppression of fluorescent emissions with nanosecond lifetime difference is proposed and illustrated in this paper. The system can give high optical sectioning and employs an algorithm for obtaining phase sensitive images. The system can find main application in vivo biomedical diagnostics for detecting biochemical changes for distinguishing malignant tissue from healthy tissue.