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Genomic Sciences for Developmentalists: A Merge of Science and Practice

机译:面向发展主义者的基因组科学:科学与实践的融合

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摘要

The etiological forces of development have been a central question for the developmental sciences (however defined) since their crystallization as a distinct branch of scientific inquiry. Although the history of these sciences contains examples of extreme positions capitalizing on either the predominance of the genome (i.e., the accumulation of genetic factors driving development) or the environmentome (i.e., the accumulation of environmental factors driving development), the moderate view of development as the emergence of a person from a particular genome and within a specific context has settled into the driver’s seat and is disputed no longer. Yet, although there is a converging theoretical perspective, a gap between this perspective and practice remains. In other words, society needs to translate this position into praxis. This opinion exemplifies the current state of corresponding knowledge in the developmental sciences, with a particular emphasis on the understanding of the role of the genome in child and adolescent development, and offers a set of comments on how this translation is being shaped by the newest technologies in the genomic sciences. ? 2015 Wiley Periodicals, Inc.
机译:自从发展成科学探究的一个独立分支以来,发展的病因学力就一直是发展科学(无论如何定义)的中心问题。尽管这些科学的历史包含利用基因组的优势(即,驱动发展的遗传因素的积累)或环境基因组(即,驱动发展的环境因素的积累)发挥作用的极端立场的例子,因为一个人从特定的基因组中出现并在特定的背景下已经融入了驾驶席,并且不再受到争议。然而,尽管理论上有一个融合的观点,但这种观点与实践之间仍然存在差距。换句话说,社会需要将这一立场转化为实践。该观点例证了发展科学中相应知识的当前状态,并特别强调了对基因组在儿童和青少年发育中的作用的理解,并就最新技术如何影响这种翻译提供了一组评论在基因组科学中。 ? 2015年Wiley Periodicals,Inc.

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