How Did the Chicken Cross the Road? With Her Striatal Cholinergic Interneurons, Of Course

摘要

Recognizing when the world changes is fundamental for normal learning. In this issue of Neuron, Bradfield etal. (2013) show that cholinergic interneurons in dorsomedial striatum are critical to the process whereby new states of the world are appropriately registered and retrieved during associative learning.