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Late Presentation of Ataxia, Areflexia, and Electrophysiological Abnormalities as Part of Miller Fisher Syndrome: Case Report

机译:米勒费雪综合症的一部分,共济失调,反射力和电生理异常的晚期表现:病例报告

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摘要

Miller Fisher syndrome (MFS) is characterised by the triad of ophthalmoplegia, ataxia, and areflexia. A case with external ophthalmoplegia and absence of ataxia and areflexia until the end of second week is presented. Electrophysiological findings became apparent after the third week and showed reduced amplitudes of sensory nerve action potentials and prolonged latencies of F with no evidence of conduction blocks. There was no response to intravenous immunoglo-bulin, but there was response to corticosteroids. This case may represent an atypical MFS with late presenting electrophysiological abnormalities. Corticosteroids can be a therapeutic option when intravenous immunoglobulin fails to control clinical symptoms.
机译:Miller Fisher综合征(MFS)的特征是眼肌麻痹,共济失调和反射障碍三联征。提出了直到第二周末外眼肌麻痹和共济失调和无反射的病例。第三周后电生理学发现变得明显,并显示感觉神经动作电位的幅度降低和F的潜伏期延长,而没有传导阻滞的迹象。对静脉内免疫球蛋白无反应,但对皮质类固醇激素有反应。这种情况可能代表了非典型的MFS,晚期出现了电生理异常。当静脉内免疫球蛋白无法控制临床症状时,皮质类固醇可能是一种治疗选择。

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