A convenient synthetic route from isatin N-Mannich bases to nitrogen-containing derivatives of isoindigo

摘要

The reaction of aminomethylisatins (isatin N-Mannich bases) with hexaethylphosphorous triamide leads to the formation of 1,1'-bis(dialkylaminomethyl)-3,3'-bis(indolin-3-ylidene)-2,2'-diones and 1,1'-bis(1,3-di-oxo-1,3-dihydroisoindol-2-ylmethyl)-1H,1'H-[3,3']bisindol-ylidene-2,2'-dione.