METHOD FOR PREPARING ISOINDIGO COMPOUND BY ORGANIC CATALYTIC ISATIN SELF-CONDENSATION

摘要

The present invention relates to the technical fields of organic synthesis, dyes, pharmaceutical chemicals, organic photoelectric materials etc. Disclosed is a method for preparing an isoindigo compound by organic catalytic isatin self-condensation. In the method, isatin and derivatives are used as raw materials, an organic amine is used as a catalyst, carbonyl sulfide is introduced, and stirring is performed at 25-100 degrees Celsius for 8-24 hours to prepare a functionalized isoindigo compound. The reaction has the features of mild reaction conditions, simple operation, good functional group tolerance, high conversion rate, high yield, and good chemical selectivity. The compound has a potential application prospect in the fields of dyes, organic photoelectric materials, natural product synthesis, and pharmaceutical chemicals.