Refractory hiccups due to phenytoin therapy.

摘要

Hiccup is a sudden contraction of the inspiratory muscles, followed by an abrupt closure of the glottis. Hiccup is usually transient and resolves spontaneously but if prolonged can present a diagnostic and therapeutic challenge. Drugs are uncommonly associated with hiccups. Here, we describe a patient with epilepsy who had refractory hiccups for 2 years, while taking phenytoin.