Infectious psychosis: cryptococcal meningitis presenting as a neuropsychiatry disorder.

摘要

Sir,Among neuropsychiatry manifestations, disorders like psychosis, mania, delirium, depression and dementia are the commonest and can rarely be seen in patients with central nervous infections. One such condition is cryptococcal meningitis which can present as acute manifestation of organic brain syndrome causing impairment of cognition.A 49-year-old male, a known case of direct Coombs test-positive hemolytic anemia, presented with symptoms of psychosis, on and off fever, and headache of two months' duration. Brain computed tomography (CT) scan was normal and he was diagnosed with psychosis and was started on olanzapine 2.5 mg/day and clonazepam 0.25 mg/ day. On day 10 he returned with mild resolution of psychotic symptoms, but worsening of headache and was admitted under neurology for further workup.