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The Global Cancer Genomics Consortium: Interfacing genomics and cancer medicine

机译:全球癌症基因组学联盟:基因组学与癌症医学的衔接

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摘要

The Global Cancer Genomics Consortium (GCGC) is an international collaborative platform that amalgamates cancer biologists, cutting-edge genomics, and high-throughput expertise with medical oncologists and surgical oncologists; they address the most important translational questions that are central to cancer research and treatment. The annual GCGC symposium was held at the Advanced Centre for Treatment Research and Education in Cancer, Mumbai, India, from November 9 to 11, 2011. The symposium showcased international next-generation sequencing efforts that explore cancer-specific transcriptomic changes, single-nucleotide polymorphism, and copy number variations in various types of cancers, as well as the structural genomics approach to develop new therapeutic targets and chemical probes. From the spectrum of studies presented at the symposium, it is evident that the translation of emerging cancer genomics knowledge into clinical applications can only be achieved through the integration of multidisciplinary expertise. In summary, the GCGC symposium provided practical knowledge on structural and cancer genomics approaches, as well as an exclusive platform for focused cancer genomics endeavors.
机译:全球癌症基因组学联盟(GCGC)是一个国际协作平台,将癌症生物学家,前沿基因组学和高通量专业知识与医学肿瘤学家和外科肿瘤学家融合在一起;他们解决了对癌症研究和治疗至关重要的最重要的翻译问题。一年一度的GCGC研讨会于2011年11月9日至11日在印度孟买的癌症治疗研究和教育高级中心举行。该研讨会展示了探索癌症特异性转录组变化,单核苷酸的国际下一代测序工作。多态性和各种癌症类型的拷贝数变异,以及开发新的治疗靶标和化学探针的结构基因组学方法。从研讨会上提出的研究范围来看,很明显,只有通过整合多学科专业知识,才能将新兴的癌症基因组学知识转化为临床应用。总之,GCGC座谈会提供了有关结构和癌症基因组学方法的实践知识,以及专注于癌症基因组学研究的独家平台。

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