IBD: Regular, prolonged aspirin use and an increased risk of Crohn's disease.

摘要

People who regularly take aspirin for a prolonged period of time are six times more likely to develop Crohn's disease. "In a middle-aged to elderly population, aspirin use may be relevant in nearly 1 in 5 cases of Crohn's disease," explains Simon Chan, corresponding author.Experimental data support the role of NSAIDs as a causative risk factor for IBD. In addition, three epidemiological case-control studies found an association between NSAID.use and an increased risk of IBD; however, recall bias could not be ruled out. These studies also included the use of any NSAID and considered IBD as a whole.