Effects of SNP in TSH-beta Gene of Chicken on Economic Traits

摘要

Thyroid hormone (TH) plays a role in growth of the poultry. Thyroid-stimulating hormone (TSH) stimulates production and distribution of TH, and is a heterodimer which is formed by a- and beta-subunits. Most of TSH activity is known to rely on beta-subunit. TSH-beta gene is located on chicken chromosome 26 and associated with growth performances. Therefore, this study aimed to investigate the association of TSH-beta SNP (G1031C) with economic traits (layday, layw, layno, bwl50, bw270, layw270) in Korean Native Black chicken, Rhode Island Red and Cornish. Allele frequency of GG genotype in Rhode Island Red (RIR) was found to be 1.00 in this study. A significant effect was only observed on body weight at day 150 in Cornish. In Cornish, body weights ofchicken with the CC genotype (302.15 ± 6.336) were significantly higher than that of the GG genotype (294.56 ± 4.537) (p<0.05). These findings suggest that the G1031C SNP of TSH-beta gene can be used for improvement of growth-related traits in Cornish.