Severe hand sanitiser (isopropanol) toxicity managed with continuous venovenous haemodiafiltration and angiotensin II

摘要

We present a case of a patient who ingested an isopropanol based hand sanitiser and developed severe CNS depression and cardiovascular collapse which was treated with continuous venovenous haemodiafiltration (CVVHDF) and angiotensin II.A 44-year-old female presented to the emergency department (ED) intoxicated and with suicidal ideation.Approximately 5.5 h earlier she had ingested 5mg diaze-pam and an unknown amount of ethanol.Initial examination on ED arrival revealed a blood pressure of 115/80mmHg, pulse 104 bpm,normothermia (36.4 Celsius), oxygen saturations 98 on room air, a GCS 14 (E3-4, V1-4, M6), and breathalyser ethanol concentration of 0.135.