After the invention of the microscope by Antoni van Leeuwen-hoek in the 1670's, having observed and described protozoa, bacteria, spermatozoa, and red blood cells, it has since then become a useful tool found in virtually every biological laboratory. The ability to study the development, organization, and function of unicellular and higher organisms and to investigate structures and mechanisms at the microscopic level has allowed scientists to better grasp the often misunderstood relationship between microscopic and macroscopic behavior. Further, imaging specimens through a microscope preserves the temporal and spatial relationships between cellular components that are frequently lost in traditional biochemical techniques and produces a two- or three-dimensional resolution that other laboratory methods cannot.
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机译：在1670年代安东尼·范·利文·霍克（Antoni van Leeuwen-hoek）发明了显微镜之后，该显微镜观察并描述了原生动物，细菌，精子和红细胞，从那时起，它已成为几乎每个生物学实验室都发现的有用工具。研究单细胞和高等生物的发育，组织和功能以及在微观水平研究结构和机制的能力使科学家能够更好地把握微观和宏观行为之间经常被误解的关系。此外，通过显微镜对标本成像可以保留传统生化技术中经常丢失的细胞成分之间的时空关系，并产生其他实验室方法无法获得的二维或三维分辨率。
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