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A report of the 2000 and 2001 Paternity Testing Workshops of the English Speaking Working Group of the International Society for Forensic Genetics.

机译:国际法医遗传学会英语工作组2000年和2001年亲子鉴定工作坊的报告。

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摘要

During the last 10 years, the English Speaking Working Group (ESWG) of the International Society for Forensic Genetics (ISFG) has once a year arranged a Paternity Testing Workshop in which blood samples as well as a questionnaire concerning laboratory strategies were distributed to the participating laboratories. In 2000 and 2001, paper challenges were included in the workshops. Here, we present the results of the 2000 and 2001 Paternity Testing Workshops. The numbers of participating laboratories were 33 (2000) and 36 (2001). A total of 36% (2000) and 31% (2001) of the laboratories submitted typing results of variable number of tandem repeats (VNTRs) investigated with restriction fragment length polymorphism (RFLP) and single locus probes (SLPs). A total of 91% (2000) and 86% (2001) submitted typing results of polymerase chain reaction (PCR) based systems. Typing errors occurred in 0.3% of the submitted PCR-based results in 2000 and in 0.1% in 2001. The results of the paper challenges showed a high degree of variation in the formulas used for calculation of the weight of evidence of rare events such as inconsistencies or possible silent alleles. The majority of the laboratories used the same formulas for calculations of frequently occurring events.
机译:在过去的10年中,国际法医遗传学会(ISFG)的英语工作组(ESWG)每年安排一次亲子鉴定工作坊,向参加者分发血样以及有关实验室策略的问卷实验室。在2000年和2001年,讲习班中包括了纸质挑战。在这里,我们介绍了2000年和2001年亲子鉴定工作坊的结果。参与实验室的数量为33个(2000年)和36个(2001年)。共有36%(2000)和31%(2001)的实验室提交了使用限制性片段长度多态性(RFLP)和单基因座探针(SLP)研究的可变数目的串联重复序列(VNTR)的打字结果。共有91%(2000)和86%(2001)提交了基于聚合酶链反应(PCR)的系统的打字结果。打字错误发生在2000年提交的基于PCR的结果的0.3%和2001年的0.1%。论文挑战的结果表明,用于计算罕见事件(例如,不一致或可能的沉默等位基因。大多数实验室使用相同的公式来计算频繁发生的事件。

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