Two new cerebrosides from the pollen of Typha angustifolia

摘要

Two new cerebrosides, 1-O-(beta-D-glucopyranosyloxy)-(2S,3S,4R,8Z)-2-[(2'R)-2'-hydroxytricosanoylamino]-8-nonadecene-3,4-diol (1) and 1-O-(beta-D-glucopyranosyloxy)-(2S,3R,4E,8Z)-2-[(2'R)-2'-hydroxynonadecanoylamino]-4,13-nonadecene-3-diol (2), were isolated from the pollen of Typha angusitfolia Their structures were elucidated by chemical and spectral means. This is the first report on the occurrence of cerebroside in Typha (Typhaceae) Compounds 1 and 2 exhibited effect on the proliferation of cultured vascular smooth Muscle cell (VSMCs) induced by fatal bovine serum (FBS)