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Facial paralysis: research and future directions.

机译:面瘫:研究和未来方向。

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Facial paralysis has fascinated physicians through the centuries. Management of the condition has evolved extensively over the past 50 years, relying largely upon neural repair techniques and static techniques prior to the 1940s, followed by heavy emphasis on regional muscle transfer by the 1970s. With the advent of the operating microscope and the development of microinstrumentation, in the mid-1970s free tissue transfer became technically feasible, and new techniques quickly ensued that introduced functioning muscle as a viable and valuable option in the management of the paralyzed face. These techniques have been subject to continual refinement to improve their reliability and reduce morbidity. In the modern era of evidence-based medicine, the field of facial nerve management has expanded exponentially with critical questions that will help future facial reanimation surgeons refine the approach for patients with acute and long-standing facial paralysis. This article will discuss current research areas with respect to assessment and management of the facial nerve patient, as well as future surgical outcomes. We will also present the state of both clinical research and contemporary basic science issues relevant to facial nerve disorders.
机译:几个世纪以来,面瘫使医生着迷。在过去的50年中,病情的管理已发生了广泛的变化,在很大程度上依赖于1940年代之前的神经修复技术和静态技术,随后在1970年代重点转向局部肌肉转移。随着手术显微镜的出现和微仪器的发展,在1970年代中期,自由组织转移在技术上变得可行,并且紧随其后的新技术是将功能性肌肉引入治疗瘫痪面部的可行且有价值的选择。对这些技术进行了不断完善,以提高其可靠性并降低发病率。在现代循证医学时代,面神经管理领域以关键问题成倍增长,这些关键问题将帮助未来的面部复健外科医生完善急性和长期性面瘫患者的治疗方法。本文将讨论有关面神经患者评估和治疗的当前研究领域,以及未来的手术结局。我们还将介绍与面神经疾病有关的临床研究和当代基础科学问题的现状。

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