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首页> 外文期刊>Gut: Journal of the British Society of Gastroenterology >Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas
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Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas

机译:肿瘤免疫力的特征区分亚洲和非亚洲人胃腺癌

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摘要

Objective Differences in gastric cancer (GC) clinical outcomes between patients in Asian and non-Asian countries has been historically attributed to variability in clinical management. However, recent international Phase III trials suggest that even with standardised treatments, GC outcomes differ by geography. Here, we investigated gene expression differences between Asian and non-Asian GCs, and if these molecular differences might influence clinical outcome.
机译:客观上,亚洲国家和非亚洲国家患者在胃癌(GC)临床结局方面的差异历史上一直归因于临床管理的差异。但是,最近的国际III期临床试验表明,即使采用标准化治疗方法,GC的结果也因地理位置而异。在这里,我们研究了亚洲和非亚洲GC之间的基因表达差异,以及这些分子差异是否会影响临床结果。

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