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Droplet-based Microfluidics: Sensitive Detection of Rare Mutations

机译:基于液滴的微流体:罕见突变的灵敏检测

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摘要

In oncology, the success of treatment against a specific cancer is linked to the ability to detect tumor cells as early as possible: early diagnostics are essential part in the fight against cancer. In that respect, there is a need for sensitive methods to find traces of cancer biomarkers in samples coming from patients. A vision for the future of cancer diagnostics would be based on the analysis of bodily fluids to find these biomarkers. A high sensitivity is there a strong pre-requisite to be able to distinguish genetic alterations at the level of traces in such samples.
机译:在肿瘤学中,成功治疗特定癌症与尽早发现肿瘤细胞的能力有关:早期诊断是抗击癌症的重要组成部分。在这方面,需要一种灵敏的方法来发现患者样品中癌症生物标记物的痕迹。未来癌症诊断的愿景将基于对体液的分析以找到这些生物标记。高灵敏度是能够在此类样品中痕量水平上区分基因改变的强大先决条件。

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