Practicable Synthesis of 1-(1-Phenylethyl)-1H-pyrido[2,3-b][1,4]oxazine

摘要

The benzo[1,4]-oxazine ring system executing an important template has attracted considerable interest in the search for novel pharmaceutical compounds,but their pyridine derivatives were rarely mentioned in the literature.Only very few like synthesis of 2H-pyrido[3,2-b][l,4]oxazine,pyrido[4,3-b][1,4]oxazine and 4-acetyl-3(R)-and 3(S)-(hydroxymethyl)-3,4-dihydro-2H-pyrido[3,2-b]oxazine were reported.