Detect Rare Alleles in NGS with MolecularTags:ThruPLEX@Tag-seq Kit Reduces False Positives for Discovery of True Mutations

摘要

Research in next-generation sequencing (NGS) is rapidly evolving, especially in several areas of cancer research that rely on detection of mutations. In contrast to germline mutations, somatic mutations may be present at low frequencies within an excess of DNA from normal cells.