The Hill-Robertson effect is a consequence of interplay between linkage, selection and drift: a commentary on 'The effect of linkage on limits to artificial selection' by W. G. Hill and A. Robertson

摘要

Using simulation, I had found that his formulae overpredicted the effect of mass selection on Ne, but (annoyingly) did not realize why. Wray & Thompson (1990) identified the key point that, as selection increases the population mean in the next generation, the selective advantage transmitted to offspring of selected individuals is less than one-half, because their competitors are also better.