In depression, increased psychological reactance is associated with poorer treatment compliance

摘要

Context: Although it is a challenge to successful treatment of depression, medication non-adherence is a prevalent phenomenon. There is evidence that attitudes and beliefs are at least as important as side-effects in predicting adherence. Evidence from a systematic review has shown inconsistent associations between sociodemographic or clinical variables and adherence. Thus, this study by De Las Cuevas and colleagues focuses on atti-tudinal predictors of poor adherence to antidepressant treatment, namely the joint effects of control beliefs, a sense of self-efficacy and psychological reactance resulting from an individual's perception that his/her freedom of choice is threatened.