Novel method of stent insertion for malignant lower rectal obstruction with proximal releasing delivery system (with video)

摘要

Background Self-expandable metal stents are an alternative to preoperative and palliative colostomy for patients with malignant colorectal obstruction. However, self-expandable metal stent placement is considered unsuitable or contraindicated for patients with malignant lower rectal obstruction within 5 cm of the anal verge because the exposed stent portion can irritate the distal rectum and cause anal pain and a foreign body sensation. Objective To describe our experience with 6 patients with malignant lower rectal obstruction who underwent stent insertion with a proximal releasing delivery system (PRDS). Design Prospective clinical series outcome study. Setting A tertiary-care referral university hospital. Patients This study involved all patients at our center who had a malignant lower rectal obstruction within 5 cm of the anal verge caused by rectal cancer and bladder cancer. Intervention Uncovered stent with the PRDS with endoscopic and fluoroscopic guidance. Main Outcome Measurements Technical and clinical success rate, adverse event rate, and stent migration rate. Results All stents were placed at the expected location. Technical and clinical success rates were 100%. Two patients reported anal pain, which was controlled with analgesics. One case of tumor ingrowth occurred after 5 months and was treated with reinsertion of a stent with the PRDS. After stent insertion, the patients received chemotherapy, chemoradiotherapy, or conservative care. Limitations Small number of patients and no comparison group. Further prospective, randomized, controlled trials are needed. Conclusions Uncovered stent insertion with the PRDS is a feasible, safe, and effective treatment for the patient with malignant lower rectal obstruction within 5 cm from the anal verge.