EUS-guided 19-gauge trucut needle biopsy for diagnosis of lymphoma missed by EUS-guided FNA.

摘要

Since its introduction in the early 1990s,1 EUS-guided FNA (EUS-FNA) has been used for sampling of extraintesti-nal mass lesions and peri-intestinai lymphadenopathy.2" Although EUS-FNA is highly accurate, certain neoplasms, such as lymphoma and Gl stromal tumors, and well-differentiated pancreatic adenocarcinoma can be challenging to diagnose by EUS-FNA.5 More recently, EUS-guided 19-gauge trucut biopsy (EUS-TCB) has been introduced. A few reports suggest that it might have a niche in diagnosing a variety of submucosal and mediastinai lesions, especially when tissue fragments, as seen in biopsy specimens, rather than singie celis and when cell groups, as seen in cytology smears, are required to further correctly characterize the lesion.