Comment on: Think to prevent before than to treat renal impairment in multiple myeloma: Do not forget tubular damage mimicking Fanconi syndrome

摘要

In a recent paper, renal impairment is correctly described as a common complication of symptomatic myeloma (20 - 40%) needing dialysis. Significant improvement has been attributed to novel therapeutic chemotlierapy regimens coupled with extrarenal free light chain removal obtained by plasma exchange or dialysis . As nephrologists, we would like to stress the importance of recognizing early symptoms of renal impairment other than by measuring renal function as glomeru-lar filtration rate (GFR) [2]. An increase in serum creatinine and/or a decrease in GFR are not the only markers of renal impairment in patients with multiple myeloma.