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Image quality of ultra-low radiation exposure coronary CT angiography with an effective dose <0.1 mSv using high-pitch spiral acquisition and raw data-based iterative reconstruction.

机译:使用高螺距螺旋采集和基于原始数据的迭代重建,有效剂量<0.1 mSv的超低辐射暴露冠状动脉CT血管造影的图像质量。

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We evaluated the potential of prospectively ECG-triggered high-pitch spiral acquisition with low tube voltage and current in combination with iterative reconstruction to achieve coronary CT angiography with sufficient image quality at an effective dose below 0.1 mSv.Contrast-enhanced coronary dual source CT angiography (2?×?128?×?0.6 mm, 80 kV, 50 mAs) in prospectively ECG-triggered high-pitch spiral acquisition mode was performed in 21 consecutive individuals (body weight <100 kg, heart rate ≤60/min). Images were reconstructed with raw data-based filtered back projection (FBP) and iterative reconstruction (IR). Image quality was assessed on a 4-point scale (1 = no artefacts, 4 = unevaluable).Mean effective dose was 0.06?±?0.01 mSv. Image noise was significantly reduced in IR (128.9?±?46.6 vs. 158.2?±?44.7 HU). The mean image quality score was lower for IR (1.9?±?1.1 vs. 2.2?±?1.0, P?75 kg.Coronary CT angiography with an estimated effective dose <0.1 mSv may provide sufficient image quality in selected patients through the combination of high-pitch spiral acquisition and raw data-based iterative reconstruction.
机译:我们评估了以低管电压和电流进行前瞻性ECG触发的高螺距螺旋采集与迭代重建相结合的潜力,以在0.1 mSv以下的有效剂量下获得具有足够图像质量的冠状动脉CT血管造影。对比增强的冠状动脉双源CT血管造影在连续21位体重(<100 kg,心率≤60/ min)的患者中以预期的ECG触发高音调螺旋采集模式(2?×?128?×?0.6 mm,80 kV,50 mAs)。使用基于原始数据的滤波反投影(FBP)和迭代重建(IR)重建图像。图像质量以4分制进行评估(1 =无伪影,4 =无法评估)。平均有效剂量为0.06?±?0.01 mSv。 IR中的图像噪声显着降低(128.9?±?46.6 vs. 158.2?±?44.7 HU)。 IR的平均图像质量得分较低(1.9±±1.1,vs 2.2±±1.0,P 0.0001)。在292个冠状动脉节段中,FBP中的55个和IR中的40个(P≥0.12)被定为“无法评估”。在FBP和IR中体重均≤75 kg的患者中,与> 75 kg的患者相比,可完全评估的节段的比率明显更高。估计有效剂量<0.1 mSv的冠状CT血管造影可以提供足够的图像质量通过高螺距螺旋采集和基于原始数据的迭代重建相结合的方式,对选定的患者进行治疗。

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