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首页> 外文期刊>European radiology >Effect of partial left ventriculectomy on left and right ventricular volumes and function as assessed with electron beam tomography: preliminary results.
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Effect of partial left ventriculectomy on left and right ventricular volumes and function as assessed with electron beam tomography: preliminary results.

机译:电子束断层扫描评估部分左心室切除术对左右心室容积和功能的影响:初步结果。

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摘要

Our objective was to determine if left ventricular reduction surgery affects left and right ventricular volumes and function. Twenty-three patients with end-stage heart failure underwent contrast-enhanced electron beam tomographic function studies before and twice after partial left ventriculectomy (PLV). The PLV was combined with other cardiosurgical procedures in 20 of 23 patients. Left and right ventricular enddiastolic volume (LVEDV, RVEDV), stroke volume (LVSV, RVSV), ejection fraction (LVEF, RVEF), and enddiastolic diameter (LVEDD, RVEDD) were determined by manual tracing of endo- and epicardial borders at enddiastole and endsystole. Patients were scanned 31 days (+/-34) before and 18 days (+/-13) and 8 months (+/-4) after PLV. Mean pre- and early and late postoperative values for LVEDV, LVSV, LVEF, and LVEDD were 387.9 ml (+/-125.5 ml), 255.6 ml (+/-79.3 ml; p<0.01), and 253.7 ml (+/-97.8 ml; p<0.05), 79.7 ml (+/-25.2 ml), 74.8 ml (+/-17.9; n.s.), and 79.1 ml (+/-26.5 ml; n.s.), 21.6% (+/-7.3%),31.9% (+/-13.4%; p<0.05), and 34.1% (+/-14.1%; p<0.05), and 72.0 mm (+/-10.6 mm), 64.3 mm (+/-8.5 mm; p<0.05), and 63.5 mm (+/-9.4 mm; p<0.05), respectively. Mean pre- and postoperative values for RVEDV, RVSV, RVEF, and RVEDD were 177.7 ml (+/-72.8 ml), 172.4 ml (+/-59.2 ml; n.s.), and 178.9 ml (+/-60.8 ml; n.s.), 60.3 ml (+/-21.6 ml), 68.8 ml (+/-19.9 ml; n.s.), and 78.3 ml (+/-25.3 ml; n.s.), 38.1% (+/-15.4%), 43.7% (+/-16.3%; p<0.05), and 45.1% (+/-11.2%; n.s.), and 50.4 mm (+/-10.9 mm), 48.1 mm (+/-8.7 mm; n.s.), and 48.5 mm (+/-9.8 mm; n.s.), respectively. The PLV may induce a significant early reduction of left ventricular volumes and improvement of biventricular function; however, our results must be judged carefully as the majority of patients in this study underwent additional cardiosurgical procedures, the contributory effect of which on the overall outcome remains unclear.
机译:我们的目的是确定左室复位手术是否会影响左,右室容量和功能。 23例末期心力衰竭患者在部分左心室切除术(PLV)之前和之后进行了对比增强电子束断层扫描研究。 23例患者中有20例将PLV与其他心脏外科手术相结合。左,右心室舒张末期容积(LVEDV,RVEDV),中风量(LVSV,RVSV),射血分数(LVEF,RVEF)和舒张末期直径(LVEDD,RVEDD)通过手动追踪舒张末期和舒张期的心内膜和心外膜边界来确定搏动末期。在PLV之前,31天(+/- 34)和18天(+/- 13)和8个月(+/- 4)扫描患者。 LVEDV,LVSV,LVEF和LVEDD的术前,术后早期和晚期平均值分别为387.9 ml(+/- 125.5 ml),255.6 ml(+/- 79.3 ml; p <0.01)和253.7 ml(+/- 97.8 ml; p <0.05),79.7 ml(+/- 25.2 ml),74.8 ml(+/- 17.9; ns)和79.1 ml(+/- 26.5 ml; ns),21.6%(+/- 7.3%) ),31.9%(+/- 13.4%; p <0.05)和34.1%(+/- 14.1%; p <0.05)和72.0 mm(+/- 10.6 mm),64.3 mm(+/- 8.5 mm) ; p <0.05)和63.5mm(+/- 9.4mm; p <0.05)。 RVEDV,RVSV,RVEF和RVEDD的平均术前和术后值分别为177.7 ml(+/- 72.8 ml),172.4 ml(+/- 59.2 ml; ns)和178.9 ml(+/- 60.8 ml; ns) ,60.3 ml(+/- 21.6 ml),68.8 ml(+/- 19.9 ml; ns)和78.3 ml(+/- 25.3 ml; ns),38.1%(+/- 15.4%),43.7%(+ /-16.3%; p <0.05)和45.1%(+/- 11.2%; ns),和50.4 mm(+/- 10.9 mm),48.1 mm(+/- 8.7 mm; ns)和48.5 mm( +/- 9.8 mm; ns)。 PLV可能会导致早期显着减少左心室容积并改善双心室功能;但是,我们的结果必须仔细判断,因为本研究中的大多数患者都接受了额外的心脏外科手术,其对总体结果的影响尚不清楚。

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