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If a partial nephrectomy could be done safely for a renal tumor, would radical nephrectomy be considered malpractice?

机译:如果可以对肾脏肿瘤安全地进行部分肾切除术,那么是否将根治性肾切除术视为不当行为?

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Until the broad-based introduction of ultrasound, the typical patient with renal carcinoma was presenting with either gross hematuria, flank pain, and/or palpable flank mass. These symptoms were obviously caused by large renal tumors often infiltrating Gerota's fascia or encompassing further anatomic barriers and invading adjacent organs. The surgical strategy aiming at complete tumor removal had to take into account a possible invasion of adjacent tissues and organs. Based on this hypothesis, Robson and coworkers (reference 1 in Weight et al. [1]) analyzed their data. This paper is usually cited when "radical nephrectomy" is advocated comprising en bloc removal of the entire tumor-bearing kidney within Gerota's fascia plus the ipsilateral adrenal gland. However, even that data, analyzed at a time way before modern imaging techniques, did not justify the mandatory removal of the ipsilateral adrenal gland. In this retrospective analysis, 3-yr follow-up was available for 51 of 57 patients and 5-yr follow-up was available for 30 patients: Involvement of the adrenal gland was found in 1 of 57 patients. Given these data, the dogma of radical nephrectomy including the removal of the ipsilateral adrenal gland was more "eminence" than evidence based.
机译:在广泛引入超声检查之前,典型的肾癌患者表现为肉眼血尿,胁腹疼痛和/或明显的胁腹肿块。这些症状显然是由大型肾肿瘤引起的,这些肿瘤通常会渗透到Gerota筋膜中,或者包含进一步的解剖学障碍并侵犯邻近器官。旨在彻底清除肿瘤的手术策略必须考虑到邻近组织和器官的可能侵袭。基于这一假设,Robson及其同事(Weight等人[1]中的参考文献1)分析了他们的数据。当提倡“根治性肾切除术”时,通常引用该论文,包括整条切除Gerota筋膜和同侧肾上腺内的整个荷瘤肾脏。但是,即使是在现代成像技术之前就曾经分析过的数据,也不能证明必须切除同侧肾上腺。在这项回顾性分析中,对57位患者中的51位患者进行了3年随访,对30位患者进行了5年随访:在57位患者中有1位发现了肾上腺受累。鉴于这些数据,根治性肾切除术的教条,包括同侧肾上腺的切除,比基于证据的更为“突出”。

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