Words of wisdom. Re: Radical prostatectomy findings in patients in whom active surveillance of prostate cancer fails.

摘要

The authors report on an analysis of 48 radical prostatectomy (RP) specimens obtained from patients with low-risk prostate cancer (PCa) who were on active surveillance (AS) for a mean period of 2.5 yr but who had switched to surgery after disease progression was seen. Inclusion of the cohort for AS was based on the following characteristics: Gleason score <6 (no pattern 4/5), prostate-specific antigen density <0.15, stage Tl c, two or fewer positive biopsy cores, and <50% single-core involvement [1].