首页> 外文期刊>European journal of cardio-thoracic surgery: Official journal of the European Association for Cardio-thoracic Surgery >Isolated surgical aortic valve replacement after previous coronary artery bypass grafting with patent grafts: is this old-fashioned technique obsolete?
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Isolated surgical aortic valve replacement after previous coronary artery bypass grafting with patent grafts: is this old-fashioned technique obsolete?

机译:先前的冠状动脉旁路移植术与专利移植术隔离后的主动脉瓣置换手术:这种老式技术过时了吗?

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AIM: High-risk patients are currently being evaluated for various catheter-based aortic valve replacement (AVR) techniques. To identify an individual patient's risk, scores such as the EuroSCORE or STS risk calculator (RC) are used. The aim of the present study was to evaluate the surgical results in patients who underwent isolated AVR via a median re-sternotomy after prior CABG. PATIENTS AND METHODS: Between 01/96 and 01/08, 349 patients underwent AVR as a redo procedure. One hundred and thirty patients had undergone previous CABG; in 39 patients (29 male, median age 75 (60-84)) preoperative coronary angiography revealed open grafts with no need for additional revascularization (30 had LIMA grafts). These patients underwent isolated AVR. Operative mortality was calculated using the standard and logistic EuroSCORE, and the STS RC. RESULTS: Operative (30-day mortality) was 5% (2 patients). Mean calculated predicted mortality rates for the cohort were: 12+/-3% for the standard, and 32+/-21% for the logistic EuroSCORE, and 10+/-4% according to the STS RC. Receiver operated characteristics (ROC) analysis revealed 100% specificity for standard EuroSCOREs up to 12.5%, logistic EuroSCOREs up to 39.7% and up to 17.45% for STS RC, with a sensitivity of 69.5%, 75% and 97.2%, respectively. The STS RC showed significant better prediction of mortality than the EuroSCOREs (p=0.006). CONCLUSIONS: Conventional AVR as a redo procedure after CABG with patent grafts can be performed with excellent results and lower mortality than estimated. Results of newer catheter-based AVR approaches should not to be compared with artificial scores to justify high morbidity rates.
机译:目的:目前正在对高危患者进行各种基于导管的主动脉瓣置换(AVR)技术的评估。为了识别单个患者的风险,使用了诸如EuroSCORE或STS风险计算器(RC)之类的评分。本研究的目的是评估在接受CABG后通过中位再胸骨切开术进行孤立AVR的患者的手术效果。患者和方法:在01/96至01/08之间,有349例患者接受了AVR作为重做程序。 130名患者曾经接受过CABG治疗;在39例患者中(29例男性,中位年龄75(60-84)岁),术前冠状动脉造影显示开放的移植物不需要额外的血运重建(其中30例使用LIMA移植物)。这些患者接受了孤立的AVR。使用标准和后勤EuroSCORE和STS RC计算手术死亡率。结果:手术(30天死亡率)为5%(2例患者)。根据STS RC,该队列的平均计算的预测死亡率为:标准为12 +/- 3%,逻辑EuroSCORE为32 +/- 21%,以及10 +/- 4%。接收者操作特征(ROC)分析显示,对于高达12.5%的标准EuroSCORE,针对STS RC的后勤EuroSCORE,特异性高达100.%,对STS RC的特异性高达39.7%和17.45%,灵敏度分别为69.5%,75%和97.2%。 STS RC显示的死亡率预测比EuroSCORE更好(p = 0.006)。结论:使用CABG进行专利移植后,传统的AVR作为重做程序可以实现出色的结果,并且死亡率低于估计值。不应将基于导管的新型AVR方法的结果与人工评分进行比较,以证明高发病率。

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