S9. Energy metabolism, cancer risk, and cancer prevention

摘要

Large-scale population studies have established that excess body weight is associated with increased risk of subsequent cancer mortality. Further work has shown that this is not simply related to a relationship between body size and cancer risk. Rather, it involves for many cancers a combined increase in risk with a worsening of prognosis, such that the effect of obesity on cancer-specific mortality is for many cancer types greater than the effect on risk. Given the magnitude of the global "obesity epidemic", the relationship of body size to cancer mortality deserves our attention.