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Osteoporotic Vertebral Fractures

机译:骨质疏松性椎体骨折

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摘要

Due to a demographic increase in patients with osteoporosis the epidemiology of vertebral fractures changes. Osteoporosis is characterized by low bone density, microar-chitectural deterioration of bone tissue and impaired bone strength, which leads to an increased bone fragility and susceptibility to fracture. Asymptomatic vertebral deformity was found to be associated with subsequent risk of symptomatic fractures, particularly vertebral fracture, and increased risk of mortality after a fracture. After the first osteoporotic fracture at any site the riskfor further fractures increases dramatically.Osteoporosis represents, besides the origin of such vertebral fractures and impaired bone healing,a problem in osteofixation and implant stability in fracture treatment in orthopedic surgery. Two new treatment strategies of percutaneous vertebro-and kyphoplasty have gained worldwide attention in the treatment of osteoporotic vertebral fracture and short-term observational studies and case-control studies indicate that the results are favorable, regarding both pain relief and functional status. Actually, it cannot be decided whether the internal application of bone cement to the vertebral body is effective in the long run.Special attention has to be given to the underlying osteoporosis in order to reduce the incidence of further fractures in the patients at risk. Diagnosis and treatment of osteoporosis have to be part of the treatment concept of osteoporotic vertebral fractures. Thus, it is important that orthopedic surgeons identify, assess and treat patients with fragility fractures for osteoporosis according to the currently available treatment protocols.
机译:由于骨质疏松症患者的人口增长,椎骨骨折的流行病学发生了变化。骨质疏松症的特征是骨密度低,骨组织的微结构退化和骨强度受损,从而导致骨脆性增加和易于骨折。发现无症状椎骨畸形与随后的症状性骨折,特别是椎骨骨折的风险以及骨折后死亡的风险增加有关。在任何部位发生第一次骨质疏松性骨折后,进一步骨折的风险都会大大增加。骨质疏松症不仅代表这种椎骨骨折的起源和受损的骨愈合,还代表整形外科骨折治疗中的骨固定和植入物稳定性问题。经皮椎体和后凸成形术的两种新的治疗策略在骨质疏松性椎体骨折的治疗中已获得世界范围的关注,短期观察研究和病例对照研究表明,无论是在缓解疼痛还是在功能状态方面,结果都是令人满意的。实际上,长期内不能确定骨水泥内部应用是否有效。必须特别注意潜在的骨质疏松症,以减少高危患者进一步骨折的发生率。骨质疏松症的诊断和治疗必须成为骨质疏松性椎体骨折治疗概念的一部分。因此,重要的是,骨科医生必须根据当前可用的治疗方案,识别,评估和治疗患有脆性骨折的患者的骨质疏松症。

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