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The utility of shock index in differentiating major from minor injury.

机译:休克指数在区分主要伤害和轻微伤害中的用途。

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OBJECTIVE: The importance of early recognition of hemorrhagic shock and its effects on outcome have long been recognized. Traditional vital signs are relatively insensitive as early diagnostic markers of hemorrhage. The shock index (SI); heart rate (HR) divided by systolic blood pressure (SBP), has been suggested as such a marker. We tested the diagnostic utility of the SI in differentiating major from minor injury in trauma patients. METHODS: Retrospective study of a prospectively collected observational cohort at a level I trauma center. Demographics, injury mechanism, HR, SBP, base deficit and lactate were recorded and Injury Severity Score were calculated. Major injury was defined as either a change in hematocrit greater than 10 or blood transfusion requirement during initial 24 h, or Injury Severity Score greater than 15. RESULTS: One thousand four hundred and thirty-five trauma patients were enrolled, average age 35.2+/-16.9 years. Two hundred and forty-two were classified as major injury. The area under the receiver operator characteristic curves for SI [0.63 95% confidence interval (CI) 0.59-0.67] was significantly less than that for base deficit (0.72, 95% CI: 0.69-0.76) or lactate (0.69, 95% CI: 0.65-0.73). The diagnostic performance of SI was slightly better than HR (0.58) but not SBP (0.61). To reach sensitivity of 90%, the SI must be 0.5, well in the range of a normal SBP and HR. CONCLUSION: The SI can be a valuable tool, raising suspicion when it is abnormal even when other parameters are not, but is far too insensitive for use as a screening device to rule out disease. A normal SI should not lower the suspicion of major injury.
机译:目的:早就认识到失血性休克及其对预后的影响。传统的生命体征作为出血的早期诊断指标相对不敏感。冲击指数(SI);已建议将心率(HR)除以收缩压(SBP)。我们测试了SI在区分创伤患者的重伤和轻伤中的诊断作用。方法:对一级创伤中心前瞻性收集的观察队列进行回顾性研究。记录人口统计学,损伤机制,HR,SBP,基础缺陷和乳酸,并计算损伤严重度评分。严重损伤的定义为:最初24小时内血细胞比容变化大于10或需要输血,或损伤严重度得分大于15。结果:招募了145例创伤患者,平均年龄35.2 + / -16.9年。 242次被分类为重大伤害。 SI [0.63 95%置信区间(CI)0.59-0.67]的接收器操作员特征曲线下的面积显着小于基本亏缺(0.72,95%CI:0.69-0.76)或乳酸(0.69,95%CI)的面积。 :0.65-0.73)。 SI的诊断性能略好于HR(0.58),但不及SBP(0.61)。为了达到90%的灵敏度,SI必须为0.5,并且在正常SBP和HR范围内。结论:SI可能是一种有价值的工具,即使在其他参数均未异常的情况下,如果出现异常也会引起怀疑,但是对于用作排除疾病的筛查设备而言,它太不灵敏了。正常的SI不应降低对重大伤害的怀疑。

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