Presented here is a case of chronic paracoccidioidomycosis that occurred in a Cuban female living in Austria and was first misdiagnosed as tuberculosis. The clinical picture was one of progressive pulmonary insufficiency with fever, weight loss and productive cough. Since antituberculous therapy was started but did not achieve a long-term clinical response, an intensive diagnostic work-up was performed. Paracoccidioides brasiliensis was then diagnosed by histopathology, serology, microbiology and molecular identification. Antifungal therapy was commenced immediately with amphotericin B (1 mg/kg/day) for 10 days, followed by voriconazole (200 mg/day po) for at least 3 months, and the lesions disappeared almost completely. This report presents the first published case of imported paracoccidioidomycosis in a female patient in Austria.
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机译：这里介绍的是一例慢性副球虫病，发生在居住在奥地利的一名古巴女性，最初被误诊为肺结核。临床表现为进行性肺功能不全伴发烧，体重减轻和生产性咳嗽之一。由于抗结核治疗已开始但未取得长期的临床反应，因此进行了深入的诊断检查。然后通过组织病理学，血清学，微生物学和分子鉴定对巴西副球菌进行诊断。立即用两性霉素B（1 mg / kg /天）开始抗真菌治疗10天，然后伏立康唑（口服200 mg /天）至少3个月，并且病变几乎完全消失。本报告介绍了奥地利女性患者中首例进口的副球菌类真菌病。
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