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Monitoring and treating haemodynamic disturbances in critically ill neonatal foals. Part 2: Assessment and treatment

机译:监测和治疗危重新生儿马驹的血流动力学障碍。第2部分:评估和治疗

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Assessment and treatment of haemodynamic disturbances are closely linked. The response to the previous treatment is the most reliable guide to further therapy and is especially important if direct cardiovascular monitoring is limited. Treatments should always be adapted if the intended response is not achieved. Fortunately, the rapid response of the cardiovascular system to change and the short half-life of many of the drugs used in critical care allow rapid appraisal of each therapeutic intervention, permitting a step-wise approach to treatment. One caveat is that the ultimate goal is adequate tissue oxygen delivery, not the correction of any measured haemodynamic variable. Therefore, assessments should include clinical and laboratory markers oftissue perfusion such as level of consciousness and blood lactate concentration, which may take hours rather than minutes for appreciable changes. In oliguric and anuric foals with little or no intrinsic renal dysfunction, restoration of urine output isoften the first sign of improved tissue perfusion.
机译:血流动力学障碍的评估和治疗密切相关。对先前治疗的反应是进一步治疗的最可靠指南,如果直接心血管监测受到限制,则尤为重要。如果未达到预期的反应,则应始终调整治疗方法。幸运的是,心血管系统变化的快速反应和重症监护中使用的许多药物的半衰期短,可以快速评估每种治疗干预措施,从而可以逐步采取治疗措施。一个警告是,最终目标是足够的组织氧输送,而不是任何测得的血液动力学变量的校正。因此,评估应包括组织灌注的临床和实验室指标,例如意识水平和血乳酸浓度,这可能需要数小时而不是数分钟的时间才能发生明显变化。在很少或没有内在的肾功能不全的少尿和无尿驹中,尿量的恢复通常是改善组织灌注的首要标志。

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