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首页> 外文期刊>Bulletin of experimental biology and medicine >Endogenous Progenitors as the Source of Cell Material for Ischemic Damage Repair in Experimental Myocardial Infarction under Conditions of Changed Concentration of Vascular Endothelial Growth Factor
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Endogenous Progenitors as the Source of Cell Material for Ischemic Damage Repair in Experimental Myocardial Infarction under Conditions of Changed Concentration of Vascular Endothelial Growth Factor

机译:血管内皮生长因子浓度变化条件下内源性祖细胞作为实验性心肌梗死缺血性损伤修复的细胞物质来源

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摘要

We studied the effect of VEGF-A in experimental myocardial infarction on attraction of progenitor cells into the regeneration zone. The appearance of CD34(+)CD45(+) cells known as low-differentiated progenitor cells was observed in the damaged myocardial tissue in the presence of a considerable excess of VEGF-A. These cells can act as precursors of mesenchymal tissues depending on the direction of differentiation.
机译:我们研究了实验性心肌梗塞中VEGF-A对祖细胞吸引到再生区的影响。在存在大量过量的VEGF-A的情况下,在受损的心肌组织中观察到了被称为低分化祖细胞的CD34(+)CD45(+)细胞的出现。这些细胞可以充当间质组织的前体,具体取决于分化的方向。

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