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首页> 外文期刊>Bulletin of experimental biology and medicine >Pharmacokinetic Properties of a New Glutamic Acid Derivative Glutaron
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Pharmacokinetic Properties of a New Glutamic Acid Derivative Glutaron

机译:新型谷氨酸衍生物谷氨酰胺的药代动力学性质

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摘要

Inhomogenous distribution of glutaron in organs and tissues was found after intravenous and peroral administration: the agent demonstrated high affi nity to organs with high degree of vascularization (lungs and heart) and elimination (kidney). Glutaron easily penetrates through the blood-brain barrier, which is consistent with its concentration in the adipose tissue.
机译:静脉和经口给药后,发现谷氨酰胺在器官和组织中的分布不均匀:该药物表现出对具有高度血管化程度(肺和心脏)和消除(肾脏)的器官的高亲和力。戊二酮很容易穿透血脑屏障,这与其在脂肪组织中的浓度一致。

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