Cadmium, chromium, and copper induce polychromatocyte micronuclei in carp (Cyprinus carpio L.)

摘要

The dramatic bioaccumulation index of metal residues in a fish body exceeds that of all other trace substance (Weis et al. 1995; Tuzen et al 2003). The high concentration of metal residues in a fish body interferes with the normal metabolism and causes catastrophic effects on the fishery resource (De Conto Cinier et al. 1998). For this reason, a number of studies have recently been conducted to examine the toxic mechanism of metal residues and search for the factors affecting the process of metal residues accumulation, release and distribution in fish organs (McGeer et al. 2000; Smet et al. 2001). Most of the studies, however, focused on effects of an individual metal residue (Riche et al, 1995). Relatively a little information was available about synergistic toxic effects induced by combinatorial treatment of several types of metal residues.