Low-dose naloxone infusion for the treatment of intractable nausea and vomiting after intrathecal morphine in a parturient.

摘要

Studies investigating the efficacy of naloxone for prophylaxis of nausea and vomiting following neuraxial morphine administration have yielded conflicting results, and no data exist regarding the use of naloxone infusion for the treatment of established postoperative nausea and vomiting (PONV). We present a case of PONV following intrathecal morphine for cesarean delivery, that was resistant to treatment with multiple agents, but responded to a low-dose naloxone i.v. infusion.