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PRINCIPAL MANIFOLDS AND GRAPHS IN PRACTICE: FROM MOLECULAR BIOLOGY TO DYNAMICAL SYSTEMS

机译:实践中的主要流形和图形:从分子生物学到动力学系统

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摘要

We present several applications of non-linear data modeling, using principal manifolds and principal graphs constructed using the metaphor of elasticity (elastic principal graph approach). These approaches are generalizations of the Kohonen's self-organizing maps, a class of artificial neural networks. On several examples we show advantages of using non-linear objects for data approximation in comparison to the linear ones. We propose four numerical criteria for comparing linear and non-linear mappings of datasets into the spaces of lower dimension. The examples are taken from comparative political science, from analysis of high-throughput data in molecular biology, from analysis of dynamical systems.
机译:我们介绍了非线性数据建模的几种应用,它们使用通过弹性隐喻构造的主流形和主图(弹性主图方法)。这些方法是Kohonen自组织图(一类人工神经网络)的概括。在几个示例中,我们显示了与线性对象相比,使用非线性对象进行数据逼近的优势。我们提出了四个数值标准,用于将数据集的线性和非线性映射比较到较低维度的空间中。这些例子来自比较政治学,分子生物学中的高通量数据分析,动力学系统分析。

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