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Cognitive stimulation therapy (CST) for people with dementia-who benefits most?

机译:痴呆症患者的认知刺激疗法(CST)谁最受益?

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Background The efficacy of cognitive stimulation therapy (CST) has been demonstrated, but little is known about the characteristics of people with dementia, which may predict a more positive response to CST. This study sought to investigate which factors may predict response to CST. Methods Two hundred and seventy-two participants with dementia took part in a 7-week CST intervention. Assessments were carried out pre-treatment and post-treatment. The results were compared with those of a previous comparable CST randomised control trial. A comparison of mean scores pre-CST and post-CST groups was undertaken, and contributing factors that predicted change in outcomes were examined. Results CST improved cognition and quality of life, and the results showed that the benefits of CST were independent of whether people were taking acetylcholinesteraseinhibitor (AChEI) medication. Increasing age was associated with cognitive benefits, as was female gender. Care home residents improved more than community residents on quality of life, but the community sample seemed to benefit more in relation to behaviour problems. Conclusions These results demonstrate that CST improves cognition and quality of life for people with dementia including those already on AChEIs. Older age and being female were associated with increased cognitive benefits from the intervention. Consideration should be given to aspects of CST, which may enhance the benefits for people with dementia who are male and those younger than 80 years.
机译:背景技术认知刺激疗法(CST)的功效已得到证实,但是对于痴呆症患者的特征知之甚少,这可能预示着对CST的积极反应。这项研究试图调查哪些因素可以预测对CST的反应。方法272名痴呆症患者参加了为期7周的CST干预。在治疗前和治疗后进行评估。将结果与以前的可比较的CST随机对照试验进行了比较。比较了CST前和CST后各组的平均评分,并检查了预测结局变化的因素。结果CST改善了认知和生活质量,结果表明CST的益处与人们是否服用乙酰胆碱酯酶抑制剂(AChEI)药物无关。年龄的增长与女性的认知能力有关。养老院居民的生活质量比社区居民提高了很多,但是社区样本似乎在行为问题上受益更多。结论这些结果表明,CST可改善痴呆症患者(包括已经接受AChEIs治疗的患者)的认知和生活质量。老年和女性与干预措施带来的认知益处增加有关。应该考虑CST的各个方面,这些方面可能会增加男性和80岁以下痴呆患者的利益。

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