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首页> 外文期刊>International Journal of Astrobiology >Correlation of a 140-year global time signature in cancer mortality birth cohorts with galactic cosmic ray variation
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Correlation of a 140-year global time signature in cancer mortality birth cohorts with galactic cosmic ray variation

机译:癌症死亡率出生队列中140年全球时间标记与银河宇宙射线变化的相关性

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摘要

An understanding of the cosmic ray modulation of life processes is critical to space exploration, evolution and current medical science. Previous evidence has implicated a role for cosmic rays in US female cancer, involving a possible cross-generational foetal effect. This study explores the global nature of that effect by examining cancer time variations for population cohorts in five countries on three continents. Age–period–cohort analysis was used to separate cohort-related effects from period-related effects, generating time signatures for comparisons among both male and female populations in the United States (US), United Kingdom (UK), Australia (AU), Canada (CA) and New Zealand (NZ). The available cancer mortality data spanned most of the 20th century for US, UK and AU, with shorter periods for CA and NZ. The longest cohort series spanned 1825 to 1965 and exhibited two peaks of higher mortality likelihood approximately 75 years apart in all countries and in both sexes. The constancy of this oscillation on three continents and both hemispheres suggests the presence of a global environmental effect. To explore a possible source for this effect, the birth cohort oscillation is shown to correlate with the variations in background cosmic radiation one generation prior to the birth cohorts. This confirms an earlier study correlating human breast cancer mortality and galactic cosmic rays. A corroborating correlation is also noted between the latitude dependences of cancer incidence in 42 countries and the intensity of background cosmic rays. The role of germ cells as a possible target of this radiation is discussed, emphasizing the amplification that must occur to make this weak radiation relevant to human health. Germ cell timing for this effect has profound implications for evolution, long-distance space travel and the colonization of planets with high background radiation.
机译:了解生命过程的宇宙射线调制对于太空探索,进化和当前医学至关重要。先前的证据暗示宇宙射线在美国女性癌症中起作用,涉及可能的跨代胎儿效应。这项研究通过检查三大洲五个国家的人群队列的癌症时间变化来探索这种效应的全球性。年龄-时段-队列分析被用来区分与队列相关的效应和与周期相关的效应,从而产生了时间标记,用于在美国(US),英国(UK),澳大利亚(AU),加拿大(CA)和新西兰(NZ)。现有的癌症死亡率数据跨越美国,英国和澳大利亚的整个20世纪大部分时间,而CA和NZ的时期较短。最长的队列研究时间跨度是1825年至1965年,在两个国家和地区,男女之间都出现了两个死亡率更高的高峰,相隔约75年。在三大洲和两个半球的这种振荡的持续性表明存在全球环境效应。为了探索这种效应的可能来源,显示了出生队列振荡与出生队列之前一代的背景宇宙辐射的变化相关。这证实了有关人类乳腺癌死亡率和银河宇宙射线的早期研究。在42个国家中,癌症发病率的纬度依赖性与背景宇宙射线强度之间也证实了相关性。讨论了生殖细胞作为这种辐射的可能靶标的作用,强调了使微弱的辐射与人体健康相关的放大作用。产生这种效应的生殖细胞时机对进化,长距离太空旅行以及高背景辐射的行星定植具有深远的意义。

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