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Outcome of phacoemulsification in patients with uveitis.

机译:葡萄膜炎患者超声乳化的结果。

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AIMS: To examine the visual outcome and identify risk factors for postoperative uveitis, macular oedema and neodymium-doped yttrium aluminium garnet (Nd:YAG) capsulotomy after phacoemulsification and intraocular lens (IOL) implantation in patients with uveitis. METHOD: This is a retrospective review of the medical records of 101 eyes of 101 patients. One eye was randomly selected for inclusion in patients who had bilateral surgery. Patients with juvenile arthritis, keratouveitis and lymphoma-associated uveitis were excluded. RESULTS: At the first postoperative and final visits, visual acuity was significantly better (p<0.001), and 64.4% and 71.3% of patients, respectively, had achieved >or=2 Snellen's lines of visual improvement. The cumulative probability of doubling of the visual angle was 52% over 6 years of follow-up, and this occurred at a higher rate in the presence of preoperative retinal or optic nerve lesions (HR (95% CI) 4.49 (1.41 to 14.29)). Within 3 months after operation, uveitis was morelikely to develop in female patients (OR (95% CI) 6.21 (1.41 to 27.43)) and in the presence of significant intraoperative posterior synechiae (OR (95% CI) 8.43 (1.09 to 65.41)); macular oedema was more likely to develop in patients who developed postoperative uveitis (OR (95% CI) 7.45 (1.63 to 34.16)). Nd:YAG capsulotomy occurred at a higher rate in patients aged
机译:目的:检查葡萄膜炎患者行超声乳化和人工晶状体植入术后的葡萄膜炎,黄斑水肿和掺钕钇铝石榴石(Nd:YAG)囊切开术的视觉结果并确定危险因素。方法:这是对101例患者101眼的医疗记录的回顾性回顾。随机选择一只眼睛纳入双侧手术患者。排除了患有青少年关节炎,角膜葡萄膜炎和淋巴瘤相关葡萄膜炎的患者。结果:在术后的第一次和最后一次就诊时,视敏度明显更好(p <0.001),分别有64.4%和71.3%的患者获得了Snellen's视线改善或≥2。在6年的随访中,视角翻倍的累积概率为52%,并且在术前存在视网膜或视神经病变的情况下发生率更高(HR(95%CI)4.49(1.41至14.29) )。术后3个月内,女性患者中葡萄膜炎的发生率更高(OR(95%CI)6.21(1.41至27.43)),并且术中存在严重的后粘连(OR(95%CI)8.43(1.09至65.41) );黄斑水肿更容易发生在术后葡萄膜炎患者中(OR(95%CI)7.45(1.63至34.16))。在55岁以下(HR(95%CI)2.28(1.06,4.93))和水凝胶IOLs(HR(95%CI)3.71(1.04至13.20)的患者中Nd:YAG囊切开术的发生率更高),并且在预防性全身性类固醇激素(HR(95%CI)0.25(0.11至0.59))和板状触觉有机硅IOL(HR(95%CI)0.23(0.08至0.64))的患者中发生率较低与三件式有机硅IOL(HR(95%CI)0.19(0.05至0.74))相比,使用聚甲基丙烯酸甲酯IOL。结论:大多数葡萄膜炎患者在超声乳化术后可提高视力,但在存在黄斑或视神经病变的患者中,视力丧失的比率增加。识别有术后并发症风险的患者应帮助患者咨询,并通过使用术前预防性糖皮质激素,仔细的IOL选择和术后密集性糖皮质激素预防这些并发症。

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