首页> 外文期刊>International journal of gynecological cancer: official journal of the International Gynecological Cancer Society >Up-Regulation of miR-204 Enhances Anoikis Sensitivity in Epithelial Ovarian Cancer Cell Line Via Brain-Derived Neurotrophic Factor Pathway In Vitro
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Up-Regulation of miR-204 Enhances Anoikis Sensitivity in Epithelial Ovarian Cancer Cell Line Via Brain-Derived Neurotrophic Factor Pathway In Vitro

机译:miR-204的上调通过脑源性神经营养因子途径体外增强上皮性卵巢癌细胞系中的失语敏感性。

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摘要

Objective Genomic loci encoding miR-204, which was predicted to target brain-derived neurotrophic factor (BDNF), were frequently lost in multiple cancer, including epithelial ovarian cancer (EOC). In this study, we aimed to find out the influence of miR-204 expression level on EOC cell anoikis sensitivity and to explore possible mechanisms of this process.
机译:客观地,编码miR-204的基因组基因座预计会靶向脑源性神经营养因子(BDNF),在包括上皮性卵巢癌(EOC)在内的多种癌症中经常丢失。在这项研究中,我们旨在找出miR-204表达水平对EOC细胞缺氧敏感性的影响,并探讨该过程的可能机制。

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