Advanced SurfaceModifications for Blood-Contacting Surfaces of Medical Devices

摘要

Surface modification of biomaterial interfaces remains an active field of research with a clear aim to enhance and retain blood compatibility of blood-contacting medical devices. Issues such as activation of coagulation pathways, altered hemostasis, inflammatory responses, and thrombosis are potential clinical complications during blood interaction with artificial surfaces that needs to be addressed when a new device is developed or there is a modification of a device or implant in the form of material, surface characteristics, shape, or function.