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A non-comparative evaluation of a chitosan gelling fibre.

机译:壳聚糖胶凝纤维的非比较性评估。

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摘要

An evaluation of chitosan gelling fibre dressing (KytoCel, Aspen Medical) was undertaken by tissue viability nurses in a large acute trust from December 2014--May 2015. The aim of this evaluation was to examine whether the gelling-fibre dressing can improve healing outcomes--reduction of bioburden and promotion of wound healing in both acute and chronic wounds that are infected or critically colonised. A total of 20 patients were recruited with acute and other complex wounds where wound infection was already established, or an excessive wound bioburden was delaying healing. Wound swabs were taken before and after dressing application between days 1, 3, 5 and 11 when clinically indicated, or at the surgical and medical teams' request. No more than two sets of swabs were taken in all patients. The evaluation incorporated three main criteria: patient baseline data, dressing performance, and patient perspective. Key findings were a significant reduction in wound size; rapid improvement of the quality of granulation tissue in 11 patients (55%), the reduction of the wound bioburden, and malodour combined with effective exudate management. The investigators also wanted to establish if there was a significant reduction in the identified bacteria from the initial wound swab results. Some patients were on systemic antibiotic therapy, their reduction in bacteria species may also be related to secondary dressings used. More robust investigation may be required to establish if the bacterial reduction was a result of the primary dressing.
机译:组织生存力护士于2014年12月至2015年5月对组织稳定性护士进行了壳聚糖凝胶纤维敷料的评估(KytoCel,Aspen Medical)。该评估的目的是检查凝胶纤维敷料是否可以改善愈合结果减少感染或严重定植的急性和慢性伤口的生物负荷并促进伤口愈合。总共招募了20例患有急性伤口和其他复杂伤口的患者,这些伤口已经确定了伤口感染,或者伤口生物负荷过大而延迟了愈合。根据临床指示或在手术和医疗团队的要求下,在敷料之前,之后的第1、3、5和11天之间取伤口拭子。所有患者均不超过两组拭子。评估纳入了三个主要标准:患者基线数据,敷料表现和患者观点。主要发现是伤口尺寸明显减少。快速改善了11例患者(55%)的肉芽组织质量,减少了伤口的生物负荷和恶臭,并进行了有效的渗出液管理。研究人员还希望确定从最初的伤口拭子结果中发现的细菌是否显着减少。一些患者正在接受全身性抗生素治疗,其细菌种类的减少也可能与所使用的辅助敷料有关。可能需要进行更强有力的研究,以确定细菌的减少是否是初次敷料的结果。

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