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Suspected white-tail spider bite and necrotic ulcers.

机译:疑似白尾蜘蛛咬伤和坏死性溃疡。

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AIM: To describe the clinical features, investigation, diagnosis and treatment of ulcers attributed to white-tail (WT) spider bites or necrotic arachnidism. METHODS: The study was a prospective case series of patients referred to the Hunter Area Toxicology Service (a tertiary referral toxicology unit servicing a population of 500 000) with an ulcer or skin lesion that had been attributed to either a suspected WT spider bite or necrotic arachnidism. Eleven patients with skin lesions or necrotic ulcers were referred between January 2000 and June 2002. RESULTS: In two patients that were inpatients in other hospitals, investigation and follow up was not possible. In both cases there was no history of spider bite and Staphylococcus aureus was cultured. In nine patients, a diagnosis other than spider bite was made following appropriate investigation and follow up, including: (i) two cases of dermatophytoses, (ii) three staphylococcal infections, (iii) one case of pyoderma gangrenosum, (iv) one case of cutaneous polyarteritis nodosa, (v) one case of Nocardia braziliensis and (vi) one infected diabetic ulcer. There was only one case where the person recalled seeing a spider bite them, but the patient did not collect the spider for identification. The median time to diagnosis was 3 weeks (interquartile range: 3-9 weeks) and 3.5 years in one case. Appropriate treatment was initiated once the correct diagnosis was made and all cases resolved. CONCLUSIONS: In this series, all cases initially referred as WT spider bites or necrotic arachnidism were found to have alternative diagnoses with appropriate investigations. This demonstrates that spider bites are an unlikely cause of necrotic ulcers and that all ulcers should be properly investigated with bacterial, fungal and mycobacterial cultures and skin biopsy for histopathology.
机译:目的:描述白尾(WT)蜘蛛咬伤或坏死蜘蛛网状溃疡引起的溃疡的临床特征,调查,诊断和治疗。方法:该研究是前瞻性病例系列,转诊至猎人区毒理学服务(服务于50万人口的三级转诊毒理学部门),其溃疡或皮肤病变归因于可疑的WT蜘蛛咬伤或坏死。蜘蛛症。在2000年1月至2002年6月之间,共转诊了11例有皮肤病变或坏死性溃疡的患者。结果:在其他医院住院的2例患者中,无法进行调查和随访。在这两种情况下均无蜘蛛咬伤史,并培养了金黄色葡萄球菌。在9例患者中,经过适当的调查和随访后,诊断为蜘蛛咬伤,其中包括:(i)2例皮肤真菌病,(ii)3例葡萄球菌感染,(iii)坏疽性脓皮病1例,(iv)1例(v)1例巴西诺卡氏菌和(vi)1例感染的糖尿病性溃疡。仅在一种情况下,该人回忆起看到蜘蛛咬过他们,但患者没有收集蜘蛛进行识别。诊断的中位时间为3周(四分位间距:3-9周),其中1例为3.5年。一旦做出正确的诊断并解决所有病例,便开始适当的治疗。结论:在该系列中,通过适当的研究发现所有最初被称为WT蜘蛛咬伤或坏死蛛网膜炎的病例具有替代诊断。这表明蜘蛛咬伤不太可能是坏死性溃疡的原因,所有溃疡均应通过细菌,真菌和分枝杆菌培养以及皮肤活检进行适当的组织病理学检查。

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